What Are the Best Supplements for Menopause | Stella
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What are the best supplements for menopause?

byDr. Lucy Wilkinson

With so many solutions promising to turn you into a well-rested, calm, and blissed-out being, do any menopause supplements work or are they a waste of money? Read our guide to the science behind natural menopause supplements, including black cohosh, red clover, evening primrose oil, soy, flax seeds, valerian, bee pollen, and devil’s claw.

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Decreasing hormones and menopause symptoms

Have you found yourself scouring the shelves of your local health food store for menopause supplements after struggling with hot flashes, erratic periods, angry outbursts, or exhaustion? Desperate for help, you end up searching for the ultimate remedy. 

Before we get into supplements for menopause, let’s take a step back and look at what’s happening to your body. Menopause symptoms are caused by decreased levels of the hormone estrogen. While estrogen’s main job is to regulate your menstrual cycle, the wide variety and the number of menopause symptoms, from hot flashes to thinning hair, demonstrate how varied its effects are throughout the body. 

Read more about the stages of menopause.

 HT is an FDA-approved treatment for menopause symptoms

Hormone therapy (HT) is prescribed by healthcare providers to treat menopausal symptoms and aims to replace the estrogen which is no longer produced by your body. This is the most common and usually, the most effective medical treatment to reduce menopause symptoms and helps many people access a much-improved quality of life. 

Various forms of HT have been tested on large groups of patients (hundreds of thousands of them) and there is a lot of data on the safety, risks, and benefits of using them. They are also produced in regulated laboratories with regular quality control testing, so the amount and quality of ingredients are closely monitored.

However, HT isn’t for everyone. Your healthcare provider may advise against using it due to certain medical conditions or risk factors. You may decide that your symptoms aren’t severe enough to warrant the possible, generally small, risks of taking this type of medication. Perhaps you are looking into the best supplements for menopause before going down the medical route – this guide will help you make an informed decision. 

Read more about HT risks and benefits.

The science and safety of supplements for menopause

While some may find natural menopause supplements useful, this type of treatment does not have the equivalent studies and data compared to HT. 

What have studies shown?

It can be extremely complicated for researchers and clinicians to decide whether a particular treatment is safe or effective. The most valued types of study are called systematic reviews or meta-analyses, which compare the results and methods of multiple trials. 

When it comes to herbal remedies for menopause, these trials have often either been very small and less reliable, or non-existent. None of the over-the-counter menopause supplements has been tested on such a wide scale as prescribed forms of HT. This means there is limited evidence of the benefits and risks of natural menopause supplements and uncertainty around their effectiveness.

Clinicians can give reasonably accurate estimates of the effectiveness, safety, and side effects of medically prescribed HT, but we do not have enough data to provide similar information about herbal remedies for menopause and other natural menopause supplements. This is why we cannot consider natural menopause supplements as safe – we simply don’t know.

The National Institutes of Health advise you to talk to your healthcare provider before trying dietary supplements. It also reminds you that just because they are described as “natural”, it doesn’t always mean they are safe to take as it depends on your personal medical history, how the supplement is prepared and the amount you take.

What natural menopause supplements are available?

The following are some of the common natural menopause supplements you might find in your local health food store or pharmacy, often suggested as the best supplements for menopause when you begin looking for herbal remedies. We’ve taken a look at some of the most recommended menopause supplements, and the science behind whether they work or not. 

Black cohosh

What is it? Black cohosh is a woodland herb of the buttercup family and is native to North America. It is said to alter the effect of estrogen on various parts of the body and was historically used by Native Americans as a traditional treatment for gynecological conditions.

Why do people use it? As well as being used as a menopause supplement, black cohosh is used for premenstrual symptoms, such as period pain, and also bone health.

Does the science back this up? There is not much information on the safety of this preparation, or which kinds of preparations work best. Much more research is needed to determine if herbs for menopause like black cohosh work to alleviate symptoms and if they’re safe to use. There is some limited evidence from small studies that black cohosh can help with vasomotor menopause symptoms – hot flashes, night sweats, and palpitations. 

Red clover

What is it? Red clover, a member of the legume family, has long been used as a folk remedy.  

Why do people use it? Red clover contains isoflavones – plant-based compounds that mimic the effect of estrogen in the body. The idea is that this mimicry helps ease menopause symptoms.

Does the science back this up? Although several small studies have found that red clover helped to improve menopause symptoms, more research is needed. Word of warning, red clover can worsen some underlying conditions, including some cancers and endometriosis. Talk to your healthcare provider.

Evening primrose oil

What is it? The evening primrose family is easy to spot thanks to its tall stems and clusters of bright yellow flowers (although some species are white, pink or red). Originally thought to have originated in Central America, evening primroses are now found worldwide.

Why do people use it? Evening primrose seed oil is sold in capsules and, purportedly, helps with eczema, diabetic neuropathy, and rheumatoid arthritis plus premenstrual disorders and breast pain.

Does the science back this up? Early evidence suggests that it is likely to be ineffective. It has not been found to help with any of the other medical conditions listed. There isn’t enough evidence to say whether evening primrose oil helps with any hormonal conditions, including menopausal symptoms.  


What is it? Soy is a popular, legume-based food often used in vegetarian and Asian cuisine.

Why do people use it? Like red clover, soy is a good source of isoflavones – also known as plant estrogens. As isoflavones have a similar structure to human estrogens, they are thought to ease menopausal symptoms.

Does the science back this up? There have been some studies into the use of soy isoflavones for menopause although the jury is still out. While a 2013 Cochrane review found no benefit, another systematic review did find an improvement in the frequency and severity of hot flashes.

Read more about menopause and hot flashes.

Flax seeds

What is it? Flax – also known as linseed – is a plant found in temperate areas. It has been cultivated and used for thousands of years, primarily as the raw material for linen.

Why do people use it? Like soy products and red clover, flax seeds contain high levels of plant estrogens. These are thought to mimic the effects of estrogen in the human body and ease menopausal symptoms.

Does the science back this up? As of yet, there is no clear evidence that flax eases menopausal symptoms. Evidence is still mixed, with early trials showing a range of results. However, flax seeds are a generally nutritious food to include in a balanced diet. They are a good source of fiber and protein and have been linked with possible improvements in blood pressure, blood sugar, and cholesterol.

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What is it? Valerian is a herb native to Europe and parts of Asia. It has been used since ancient times as it was thought to aid sleep.

Why do people use it? Valerian has long been thought to help with sleep issues, which are common during menopause, which is why it’s often recommended as a supplement for menopause.

Does the science back this up? Sadly not. A 2015 meta-analysis found that valerian did not affect sleep. A few small trials have found some improvement of severity in hot flashes with valerian use, although more research is needed.

Read more about sleep issues during menopause.

Bee pollen

What is it? Also known as bee bread or ambrosia, this is the yellow stuff that bees harvest from flowers. The exact composition varies markedly depending on the plants from which it is gathered, but bee pollen is generally thought to be rich in proteins, vitamins, minerals, and fatty acids.

Why do people use it? Bee pollen is claimed to have multiple beneficial effects on a range of conditions including menopause.

Does the science back this up? A few small studies have found improvements in vasomotor menopause symptoms with the use of bee pollen, but there is not enough evidence of benefit to routinely recommend it.  

Warning, bee pollen may cause serious reactions in those who have pollen allergies. Also, it may be contaminated with harmful substances including pesticides and other toxins.

Devil’s Claw

What is it? Native to South Africa, this herb earned its name thanks to the slightly sinister, hooked appearance of its fruit. It is also known as the grapple plant, wood spider, and hook plant.

Why do people use it? Devil’s Claw is used in traditional medicine as a painkiller, especially for back pain and arthritis. Some use it for joint pain that may be associated with menopause.

Does the science back this up? Possibly. A 2016 Cochrane review found that Devil’s Claw reduces low back pain more than a placebo, although this evidence was limited and further study is needed.

Learn more about menopause and aches and pains.

Top tips if using supplements for menopause

1. Ensure that you are using supplements safely

Talk to your healthcare provider before starting any natural menopause supplements. They will be able to tell you if any herbal remedies for menopause interfere with certain treatments you are taking or make worse any underlying health conditions you have. This is particularly important if you have any hormone-dependent conditions, including breast cancer, endometriosis, fibroids, uterine cancer, or ovarian cancer.

2. Read the label

Look for menopause supplements with quality testing seals. The FDA has established good manufacturing practices that companies must follow to help ensure the identity, purity, strength, and composition of their dietary supplements. These can prevent adding the wrong ingredient, or too much or too little of the correct ingredient, and reduce the chance of contamination or improper packaging and labeling of a product. The FDA periodically inspects facilities that manufacture supplements.

Several independent organizations offer quality testing and allow products that pass these tests to display a seal of quality assurance that indicates the product was properly manufactured, contains the ingredients listed on the label, and does not contain harmful levels of contaminants. These seals do not guarantee that a product is safe or effective.

Organizations that offer quality testing include:

3. Buy from trusted stores

Avoid shopping online – as you have no idea what you are buying – and buy from established stores.

Final word

So should you give it a go? Ultimately, this is a personal decision. As you can see, the majority of supplements have very limited evidence to support their effectiveness or confirm their long-term safety, so you may want to save your money. 

Remember to check in with your healthcare provider before using natural menopause supplements, especially if you have any doubts about your symptoms, if you have any medical conditions, or take any prescribed medicines.

If you are thinking about menopause supplements as part of a wider approach to menopause, take this time to evaluate your lifestyle and review your exercise, nutrition, sleep, and stress levels. Improving lifestyle choices has a proven, positive effect on many menopause symptoms.

Find out more about menopause on our blog and in our menopause symptoms library.

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